Prediction of gene structure
نویسندگان
چکیده
منابع مشابه
Gene Structure Prediction From ManyAttributesAdam
Considerable research eeort has been directed in recent years toward the problem of com-putationally identifying genes in DNA sequences. A fundamental component of a gene-nding system is a predictor which, when given a window of DNA sequence data, predicts whether or not it codes for protein product. In this paper we propose that mistake-driven, multiplicative-weight-update learning algorithms ...
متن کاملEvaluation of gene structure prediction programs.
We evaluate a number of computer programs designed to predict the structure of protein coding genes in genomic DNA sequences. Computational gene identification is set to play an increasingly important role in the development of the genome projects, as emphasis turns from mapping to large-scale sequencing. The evaluation presented here serves both to assess the current status of the problem and ...
متن کاملIntegrating genomic homology into gene structure prediction
TWINSCAN is a new gene-structure prediction system that directly extends the probability model of GENSCAN, allowing it to exploit homology between two related genomes. Separate probability models are used for conservation in exons, introns, splice sites, and UTRs, reflecting the differences among their patterns of evolutionary conservation. TWINSCAN is specifically designed for the analysis of ...
متن کاملGene structure prediction by linguistic methods.
The higher-order structure of genes and other features of biological sequences can be described by means of formal grammars. These grammars can then be used by general-purpose parsers to detect and to assemble such structures by means of syntactic pattern recognition. We describe a grammar and parser for eukaryotic protein-encoding genes, which by some measures is as effective as current connec...
متن کاملA multiobjective approach for gene structure prediction
Current advances in DNA sequencing technology have motivated the investigation of reliable gene identification methods, an open area currently present in bioinformatics. Gene recognition can be considered as a search problem, where many evidence sources should be combined in a scoring function that must be maximized to obtain the most likely and right gene structure in a genomic sequence. In th...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 1992
ISSN: 0022-2836
DOI: 10.1016/0022-2836(92)90130-c